Wednesday, 12 August 2020

Affron Saffron targets teen stress

15 June 2020 | News

The first clinically proven botanical to reduce anxiety and depression symptoms in teenagers may help youth in current crisis

image credits: shutterstock

image credits: shutterstock

Teenagers are one of the most vulnerable targets for stress due to the COVID-19 crisis and among the hardest hit from a mental health standpoint. Parents are seeking natural, holistic solutions for mental health for their children and themselves. Pharmactive Biotech, S.L., can now offer its affron®, all-natural saffron extract as a holistic solution for mental health for teens and other age groups.

Rising mental health risks for teenagers brought on by extended isolation

  • Results from a study of 500 participants in the University of Oxford’s “Achieving Resilience During COVID-19” (ARC) show that more than one-third of 13 to 18-year-olds reported high levels of loneliness. The study also uncovered evidence of loneliness as predicting depression and possible anxiety in the future.[1]
  • In a recent survey by the UK-based Young Minds movement of 2,111 young people with a history of mental health problems, more than half reported that the pressure brought on by the COVID-19 crisis made their mental health “a bit worse,” and nearly one third reported that it made their mental health “much worse.”[2]
  • A study by UNICEF, Australia, revealed that the threat of the coronavirus and the associated lockdown is damaging the well-being of Australian teenagers, with fewer than half saying they are “coping well.” Almost half of young people report that COVID-19 has increased their stress and anxiety.[3]


Affron is the first saffron extract (Crocus sativus L.) clinically studied on adolescents. In a randomized, double-blind, placebo-controlled study of adolescents aged 12-16 years with mild-to-moderate symptoms, affron, when taken over an 8-week period, improved anxiety and depressive symptoms in the subjects.

“Affron possesses a potent antioxidant and anti-inflammatory impact, which not only could help balance key neurotransmitters levels, such as serotonin and dopamine, but also fights the oxidative stress produced by anxiety and stress in the brain,” explains Alberto Espinel, Manager of Strategic R&D in Active and Functional Natural Ingredients for Pharmactive. “Unfortunately, investigations into the use of herbal and nutraceutical agents for youth are limited. However, they carry significant potential that has yet to be realized. This gap in scientific exploration is what inspired our study of affron with adolescents.”


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